East Windsor, NJ—A research review of the effects of curcumin on the immune system, written by 8 scientists including Founder and Chairman of Sabinsa Dr. Muhammed Majeed, has been published in Phytotherapy Research, according to a press release.
The review summarizes the results from in silico and animal studies of curcumin on viral infections, according to the press release. The review considers the coronavirus and potential mechanisms of action by which curcumin could affect it, including:
- Coronavirus enters human cells through the ACE2 receptor by attaching its spike protein; curcumin could at least partially prevent that entry, as inferred from in silico docking studies.
- Curcumin has a potential inhibitory effect on the main protease of the coronavirus, also reported in an in silico
- Curcumin is shown in several studies to be effective in pulmonary inflammation, fibrosis, and edema.
- Curcumin plays a positive role in cytokine storm conditions during viral infections.
- Curcumin can play a recuperative role in situations wherein viral infections cause cardiac and kidney damage.
- The review also covers curcumin’s role in mitigating the morbid acute respiratory distress syndrome during viral infections.
The release says that the antioxidant and anti-inflammatory properties of curcumin form the basis of this activity.
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Dr. Majeed said in the press release: “We are pleased to see this meaningful assemblage of the relevant work on curcumin published at a time when prevention and strong immunity is on the minds of people around the world. While the world anxiously awaits a permanent solution to this pandemic, it’s helpful to understand how safe herbal compounds like curcumin can support healthy immune function.”