Study: Nootropic Benefits of Sustained-Release Caffeine from Green Coffee Bean

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Portrait of happy young fitness woman running with earphones

Mumbai, India, and Morristown, NJ—OmniActive Health Technologies announced the publication of new pharmacokinetic data on its proprietary energy ingredient Xtenergy, a natural, sustained-release caffeine from green coffee bean. Published in Current Research in Behavioral Science, the study measured the bioavailability of Xtenergy compared to immediate release caffeine and the effects of Xtenergy on nootropic benefits, such as alertness and mood.

The study involved 24 healthy subjects receiving a single dose of 200 mg/capsule per day of Xtenergy or 99% immediate release (IR) caffeine. The finding, according to a release from OmniActive: IR caffeine resulted in a prompt increase in absorption that peaked within the first hour, followed by a sharp decline immediately thereafter up until 24 hours.  Xtenergy peaked around four hours, a ~325% increase vs. IR caffeine. Xtenergy remained in the blood ~21% longer than IR caffeine. Compared to IR caffeine, the ingredient was also associated with feelings of alertness and better overall mood, as well as feeling less tired, jittery, and tense.

“Since the nature of the caffeine formulation can directly influence the rate and extent of absorption of caffeine and its subsequent physiological effects, OmniActive formulated Xtenergy to release caffeine in an extended, sustained format over a period of six to eight hours,” explained Deshanie Rai, VP, Global Scientific & Regulatory Affairs for OmniActive, in the release. “This allows Xtenergy to deliver on key nootropic benefits that consumers want through the day.”

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Xtenergy is developed using a solvent-free process and the spray melt technology that involves coating caffeine granules, according to the release, which notes that the process makes Xtenergy suitable for use in tablets, powders, stick packs, and capsules.

“Not all energy is the same and the needs of the market are evolving,” said Kimberly Smith, CMO of OmniActive, in the release. “Xtenergy is a unique, branded solution that delivers benefits in multiple categories, from consumers who want sustained energy and nootropic benefits to power through the day to more niche segments, like esports and gaming, where the competitive advantage of clean energy is key. The health benefits of Xtenergy along with this new piece of science will help our customers further differentiate and standout in an increasingly crowded marketplace.”

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