Morristown, NJ—PLT Health Solutions, Inc. has received a license from the Natural and Non-Prescription Health Products Directorate (NNHPD) of Health Canada to market its ingredient AlvioLife to support respiratory health in Canada, according to a press release.

AlvioLife is a proprietary composition of extracts fromBoswellia serrata gum resin andAegle marmelosdried fruit. Published clinical work has shown that it can help improve overall respiratory health, maintain clear airways, help against environmental exposure, and sooth respiratory tissues.

The press release cites astudy from 2017,in which 36 patients were given either 200mg/day of AlvioLife or a placebo for 56 days. At the end of the trial period, the researchers found that asthma symptoms were improved by 14 days in the trial group compared with the placebo group; at the end of the 56 day trial period, the trial group saw a significant increase in IFNy, a cytokine critical for innate and adaptive immunity, and a significant decrease in IL-4, the overproduction of which is associated with inflammation and allergies.
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Claims approved for use in Canada:
  • AlvioLife helps to support lower respiratory tract health
  • AlvioLife helps to support lower respiratory tract health that includes the bronchial tubes and the lungs’ health
Dr. Barbara Davis, Head of Clinical and Regulatory Sciences for PLT Health Solutions, said in the press release that this license is an important milestone for AlvioLife—both because it opens up the Canadian market, and because of what it says about the science backing the ingredient. “Respiratory health is at the top of everyone’s minds these days. AlvioLife is an interesting ingredient both as a standalone but also as a compliment to immune support ingredients,” she said. “The anti-inflammatory effects, particularly 5-lipoxygenase (5-LOX) inhibition by AKBA and quince fruit, are responsible for its effectiveness in supporting respiratory health. Accumulating and significant evidence suggests that 5‐LOX has profound influence on the onset and progression of airway inflammation.”