Researchers at University of Minnesota measured CBD concentrations in epilepsy patients at the MINCEP Epilepsy Care clinic, who were taking 99% pure CBD capsules. The researchers compared concentrations from patients who took CBD on an empty stomach, and those who took it with a standardized fatty breakfast, and found that CBD exposure was vastly increased when taken with high-fat foods—it was increased by 400%, and the maximum amount recorded in participants’ blood increased by 14 times compared to those participants who were fasting. No cognitive differences were identified.