The study split rats into two groups. One group was treated orally with the yeast fermetate; the other was given phosphate-buffered saline. After 14 days, half the rats in each group were exposed to heat stress conditions, while the other half were kept at room temperature.
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Heat stress resulted in inhibition of tight junction proteins expression, decrease of Paneth and goblet cells, a decrease in beneficial bacteria and increase of pathogenic bacteria—but not in the rats treated with the yeast fermentate. Epicor elevated the beneficial gut bacteria, particularly butyrate-producing bacteria, significantly protecting them from the adverse effects of heat stress.The researchers concluded: “Our results will contribute to the development of new approaches to prevention of heat stress-related complications.”
