Ireland—Research from APC Microbiome Ireland at University College Cork (UCC) has put forth a novel approach to reverse aspects of age-related deterioration in the brain and cognitive function via gut microbes, according to a press release.
This latest study was performed on mice. Researchers showed that by transplanting microbes from young into old animals, they could rejuvenate aspects of brain and immune function.
Professor John F. Cryan, VP Research & Innovation, UCC, and Principal Investigator at APC, explained in the press release: “Previous research published by the APC and other groups internationally has shown that the gut microbiome plays a key role in aging and the aging process. This new research is a potential game changer, as we have established that the microbiome can be harnessed to reverse age-related brain deterioration. We also see evidence of improved learning ability and cognitive function.” However, he notes, this research is still in its early days, and more work is needed to discover if the findings can be replicated in humans.
APC Director Prof Paul Ross added: “This research of Prof. Cryan and colleagues further demonstrates the importance of the gut microbiome in many aspects of health, and particularly across the brain/gut axis where brain functioning can be positively influenced. The study opens up possibilities in the future to modulate gut microbiota as a therapeutic target to influence brain health.”