The single-center, two-month, open-label study was published in theJournal of Arthritis. It was performed on 70 patients with mild to moderate knee osteoarthritis. Patients saw statistically significant reductions in WOMAC pain, VAS pain, and Lequesne Algofunctional Index pain after only 10 days of supplementation; by the end of the study, those reductions in pain reached 52%, 49%, and 39%, respectively.